Pennsylvania is in the midst of a bed bug crisis as 2025 sees another surge in infestations across its urban centers. With the state ranking among the top in the nation for bed bug activity, five cities stand out as the epicenters of this onslaught—and are fighting back with vigorous prevention, education, and elimination campaigns.
1. Philadelphia: Ground Zero for Bed Bugs
For the second year in a row, Philadelphia holds the dubious honor of being the most bed bug-infested city in the United States. Experts attribute this to its dense population, booming travel industry, and varied housing conditions. Bed bug reports span from luxury hotels to row homes, prompting city-wide campaigns advocating regular mattress inspections, careful travel habits, and swift professional intervention.
Philadelphia’s Department of Public Health and local pest control services are urging residents to report infestations early and avoid DIY treatments, which often drive bugs deeper into walls and furniture.
2. Pittsburgh: Battling Persistent Bed Bug Clusters
Pittsburgh continues to be a significant battleground. The city’s older housing stock, high occupant turnover in apartment complexes, and resilient urban pests have required a collaborative approach. The Allegheny County Health Department fields numerous complaints each month, providing guidelines on treating mattresses, reducing clutter, encasing box springs, and using monitoring traps. Integrated Pest Management (IPM)—which combines steam, chemical, and mechanical methods—is now the city’s best-practice standard.
3. Harrisburg: Regional Response and Education
No city is immune, and Harrisburg, the state’s capital, is prominently featured on national infestation lists. The city’s multifamily housing developments and frequent resident movement make outbreaks hard to contain. Local government and Penn State Extension have prioritized educational programs to help landlords and tenants recognize signs of infestation, correctly prepare their homes for treatment, and prevent recurring outbreaks through integrated, multi-step solutions.
4. Lancaster–Lebanon–York: Interconnected Urban Spread
The adjoining cities of Lancaster, Lebanon, and York form a hotspot corridor where bed bugs travel easily between homes, hotels, and public spaces. Increased travel, regional events, and a mix of urban and rural residences have led to leapfrogging infestations. Professional pest control firms in the region use a combination of eco-friendly fungal spore treatments and targeted chemicals, depending on occupancy, and emphasize follow-up treatments to break the bed bug life cycle.
5. Wilkes-Barre/Scranton: Small City, Big Challenge
In cities like Wilkes-Barre and Scranton, the fight continues despite their smaller size. Local pest control companies report steady business as bed bugs adapt to both high-rise apartments and suburban homes. Residents are encouraged to use certified professionals—since unlicensed treatments and “bombs” often fail—and to follow post-treatment protocols, including repeat inspections and preventive mattress encasements.
How Pennsylvania is Fighting Back
Integrated Pest Management (IPM): Innovations combine heat, freeze, steam, and targeted insecticides, maximizing effectiveness and minimizing pesticide use.
Educational Outreach: Penn State Extension and local health departments run seminars, webinars, and distribute prevention kits. Public agencies teach detection, reporting, and non-chemical prevention tips.
Landlord-Tenant Partnerships: Especially in cities with aging housing stock, landlords are increasingly held responsible for prompt pest control and mandated tenant education.
Professional-Only Fumigation: Pennsylvania law allows only certified professionals to use the most advanced fumigants, ensuring safer, more effective treatments.
Pennsylvania’s largest cities are relentless in their fight against the bed bug invasion. With coordinated efforts involving health departments, universities, pest control companies, and residents, these urban centers are determined to reclaim homes—and peace of mind—one bed at a time.
Sources
[1] https://www.livenowfox.com/news/cities-have-most-bed-bugs-according-annual-study
[2] https://www.asianhospitality.com/bed-bugs-infestation-philadelphia-report/
[3] https://www.mypmp.net/top-50-most-bed-bug-infested-cities-in-the-u-s-revealed-by-terminix/
[4] https://www.alleghenycounty.us/Services/Health-Department/Housing-and-Community-Environment/Pest-Control/Bed-Bugs
[5] https://extension.psu.edu/biology-habitat-and-management-of-bed-bugs/